[D-His26]-Neuropeptide Y, human, rat_product_DataBase

Bioactivity	[D-His26]-Neuropeptide Y, human, rat is a synthetic variant of neuropeptide Y (NPY). [D-His26]-Neuropeptide Y, human, rat acts as a Y1R agonist that can prevent the development of anxiety, social impairment, and depressive symptoms, and has the potential to be used as an early intervention treatment for post-traumatic stress reactions[1].
Sequence	Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-{d-His}-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
Shortening	YPSKPDNPGEDAPAEDMARYYSALR-{d-His}-YINLITRQRY-NH2
Formula	C180H276N54O55S
Molar Mass	4108.51
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Nwokafor C, et al. Activation of NPY receptor subtype 1 by [D-His26] NPY is sufficient to prevent development of anxiety and depressive like effects in the single prolonged stress rodent model of PTSD[J]. Neuropeptides, 2020, 80: 102001.

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